08-19-2014, 07:17 PM
32)
D) Right heart failure
(correct by NBME)
Obstructive sleep apnea (OSA)/hypopnea syndrome occurs in approximately 10% of adult men and 5% of middleaged women. It is becoming increasingly clear that, in addition to excessive daytime sleepiness and snoring, OSA is associated with a variety of chronic cardiovascular sequelae, including hypertension, stroke, coronary artery disease, and sudden death.
Pulmonary hypertension is a less appreciated complication of the physiologic changes associated with OSA. Patients with OSA have been shown to have transient, sometimes severe, elevations in pulmonary arterial pressures (PAP) during sleep. Several factors associated with OSA lead to chronic hypoxia and subsequent right heart failure.
D) Right heart failure
(correct by NBME)
Obstructive sleep apnea (OSA)/hypopnea syndrome occurs in approximately 10% of adult men and 5% of middleaged women. It is becoming increasingly clear that, in addition to excessive daytime sleepiness and snoring, OSA is associated with a variety of chronic cardiovascular sequelae, including hypertension, stroke, coronary artery disease, and sudden death.
Pulmonary hypertension is a less appreciated complication of the physiologic changes associated with OSA. Patients with OSA have been shown to have transient, sometimes severe, elevations in pulmonary arterial pressures (PAP) during sleep. Several factors associated with OSA lead to chronic hypoxia and subsequent right heart failure.