Exam Experience.....i hope my suggestions help - dr_aa

[ArchivalUser]

hi benzene, sorry to hear that, it's a tough exam but u should know that u can do it, don't doubt urself, be confident that u'll do great n move on with this confidence..... when i started studying i used 2 get so depressed n wd think that this is jst not my thing n i'll never b able 2 do it bt with time u learn how to manage ur studies n u learn a new thing everytime u read ur books...so i wd suggest get step1 over with n then move 2 step2.... give kaplan 2 reading n then do UW, then take nbme n see where u stand.....im telling you i read kaplan like 5 times but evertime i wd learn something new and i was reinforcing my knowledge like that... if u know ur stuff really well, things wd come back 2 ur head during the exam n u'd b surprised that wow i still remeber this....it's such a big syllabus/course so just stick 2 it.....its undoubtedly boring, but u have do wt u gotta do.....keep clinging on to ur books no matter how much they bore u....

hi missdoc99, they'll give u earphones....they dodn't let u have anything of ur own...not even ur watch...they give u everything u need....actually my earphones helped be bigtime cz in the 1st block i could hear somebody typing and that was so bothering, then i had them on throughout the exam....

GoodLuck n GodBless

[ArchivalUser]

Hi dr-aa,
thanks for sharing your exam experience.......you are so lucky that you have such a nice wife who came with you and waited for such a long time.......I wish you all the best.
Im studing since 9 months back and my latest score in NBME6 is 550(232) .I also did UW assessment one month back and my score was 236 . Planned to take the exam on Dec. Pray for me please.
I have a request and I greatly appreciate if you can help me since Im really tired of begging ppl in this forum.
would you please send me the NBME answers if you have them?

[ArchivalUser]

NBME1
block1
1B
2C
3B
4E
5C
6A
7)I
8E
9A
10E
11D
12E
13B
14B
15B
16D
17A
18B
19C
20B
21C
22C
23E
24C
25A
26E
27F
28A
29D
30D
31D
32D
33A
34H
35A
36E
37A
38D
39B
40B
41E
42D
43B
44D
45A
46D
47C
48C
49D
50A
block2
1E
2A
3A
4C
5C
6B
7F
8D
9D
10A
11A
12D
13A
14C
15D
16H
17A
18C
19G
20B
21B
22C
23D
24C
25C
26D
27D
28C
29C
30B
31A
32F
33B
34C
35D
36B
37E
38C
39C
40A
41D
42E
43A
44A
45C
46E
47D
48C
49D
50C
block3
1B
2C
3D
4C
5A
6B
7E
8D
9B
10A
11C
12E
13A
14E
15E
16C
17E
18E
19D
20B
21B
22B
23G
24D
25E
26D
27E
28A
29E
30B
31B
32B
33A
34A
35D
36D
37B
38B
39D
40A
41A
42D
43C
42D
43C
44C
45D
46A
47D
48B
49C
50A
block4
1A
2B
3A
4F
5C
6H
7C
8A
9E
10D
11E
12B
13B
14A
15B
16E
17C
18D
19C
20A
21)I
22B
23E
24D
25B
26C
27C
28A
29D
30G
31B
32E
33E
34E
35D
36A
37A
38C
39E
40D
41D
42A
43E
44C
45B
46A
47H
48C
49C
50E

[ArchivalUser]

nbme2
block1
1B
2G
3B
4A
5D
6A
7C
8A
9C
10E
11A
12H
13D
14B
15C
16E
17C
18B
19B
20C
21D
22A
23A
24B
25A
26A
27C
28D
29B
30E
31D
32A
33B
34C
35C
36C
37E
38D
39D
40E
41C
42C
43B
44B
45B
46G
47E
48A
49E
50C
block2

1C
2A
3D
4C
5C
6C
7D
8A
9B
10E
11C
12E
13B
14A
15A
16D
17B
18B
19D
20A
21E
22A
23E
24A
25G
26A
27E
28B
29C
30A
31A
32B
33E
34D
35C
36D
37D
38F
39E
40B
41C
42D
43D
44E
45D
46D
47E
48C
49C
50C
block3
1C
2B
3B
4C
5F
6A
7B
8E
9E
10A
11C
12D
13A
14D
15E
16B
17D
18A
19B
20D
21D
22B
23D
24E
25B
26C
27D
28C
29A
30B
31A
32F
33B
34A
35B
36F
37D
38E
39B
40C
41C
42A
43B
44E
45D
46E
47D
48D
49C
50B
block4
1D
2D
3D
4E
5B
6A
7D
8E
9C
10D
11C
12A
13B
14C
15A
16C
17C
18B
19A
20E
21D
22E
23C
24C
25B
26I
27C
28D
29A
30D
31E
32F
33A
34B
35D
36D
37C
38B
39A
40B
41A
42B
43D
44C
45A
46E
47D
48C
49B
50C

[ArchivalUser]

nbme3
block1
1B
2D
3E
4A
5E
6H
7C
8A
9F
10A
11B
12A
13C
14E
15D
16C
17E
18B
19 Infectious mononucleosis
20B
21C
22A
23A
24A
25E
26C
27C
28D
29A
30C
31B
32E
33D
34E
35C
36A
37C
38D
39C
40E
41B
42A
43J
44D
45D
46B
47C
48B
49D
50C
block2
1A
2A
3D
4C
5C
6E
7E
8C
9D
10B
11G
12A
13G
14D
15C
16B
17C
18B
19D
20E
21C
22C
23C
24B
25C
26D
27B
28C
29C
30A
31C
32F
33A
34C
35C
36A
37B
38A
39C
40E
41D
42D
43D
44E
45B
46F
47B
48A
49A
50C
block3
1C
2C
3A
4C
5E
6B
7C
8J
9C
10C
11C
12A
13D
14B
15C
16E
17C
18E
19E
20D
21E
22B
23D
24A
25F
26E
27C
28F
29E
30D
31D
32C
33C
34A
35A
36D
37C
38E
39B
40E
41E
42A
43D
44E
45D
46G
47D
48E
49B
50B
block4
1C
2B
3C
4C
5E
6C
7A
8A
9C
10B
11C
12C
13A
14F
15E
16D
17C
18E
19A
20D
21B
22B
23E
24A
25C
26D
27A
28D
29B
30E
31B
32E
33B
34A
35D
36E
37A
38A
39C
40E
41F
42C
43D
44A
45E
46C
47A
48B
49C
50B

[ArchivalUser]

Thanks very much .You made me happy .In sha Allah you will get 99.

I have nbme forms .I apprecite again f you can post tha answer for NBME 5 and 6.
my email id is : aref_110@yahoo .com

again thanks a lot.

[ArchivalUser]

nbme4
Block 1
1... zinc finger motif is a DNA binding domain for steriod receptor
so A is right answer
2 McArdle disease Glycogen is there in the muscle but cant be used because
of deficievy of Glycogen phospholylase enzyme
3- Discuss
4- Tight junction are present between the cells and when they are
damaged the + discussion
5- CF is autosomal recessive disease ... the child with diease is homozygous
for CF gene.. carrier are heterogygous for the mutation...
For the parent to produce a homozygous child they must both be carrier of the
CF.
discuss
6- We are transplanting gene in the bone marrow so is cant be structural gene
and the probable answer could be B
7- here its cant be sarcoma becasue vimentin antibodies reaction are
negative... only clue is keratin antibodies as in squamous cell ca
there is keratin pearls so E seem to be right
8 BE SURE THAT YOU UNDERSTAND THE PROBLEM so its better to get more info rather
going to fast...........
9-He is without food from the last one week... note he consumed his food in
the first two weeks. A is wrong as no diet is there
hepatic glycogen store are for the first few hours.skeletal muscle
glycogen cant be used because of abscence of glucose 6 phosphatase
enzyme in muscle
D is the correct answer .. muscle protein are being used by the
gluconeogenesis process
urea nitrogen cant help
10- D is the correct
11-Bleomycin causes pulmonary fibrosis mean a restrictive lung disease
in restrictive lung diease either there is increase in FEV1/FVC ratio or
there is no change in it..... total lung volume decrease as there is
restriction in filling the lungs to there capacity
please add what will be the effect of diffusing capacity
C is the answer
12-AZT is reverse transtriptase inhibitor so E is right
13- urease is the answer but what is the substrate of urease and what
the product??
14-Broad base point to blastomycosis
15-these are sign of acute cholecystitis so E is right
16-this is acute rejection as occur after weeks of transplantations...
so T lymphocyte play there role
17-need explanations
18 need explanations
19-TNF is produced in response to Endotoxin and then TNF causes release
of NO which is the main mediator of shock and hypotension
20-D dimer are specific for DIC , D dimer can only assay the cross linked
fibrin monomer while FDP assay detect all the product of plasmin cleave
of fibrenogen and insloluble fibrin clots
21-H lateral corticospinal tract....what is at G position?
22-diagram is not clear any way they terminate at thalamus
23- A neostigmine inhibiot the enzyme
24- B is right DM causes accumulation of sorbitol in the schwann cell
becuase of ALDOSE REDUCTASE ENZYME which convert glucose into
sorbitol and lead to osmotic damage to the shwaan cell and
defective myelination of peripheral nerve and so peripheral
neuropathy..........
25-need explanations from net
26-C anti psychotic drug SE
27-what is the diagnosis?????????
28-iliopsoas
29-need net help
30-B
31-case of asthma which is an obstructive lung diseas FEV1. FVC is typically
decreased and residual volume is increased
32-superior vena cava syndrome due to small cell lung carcinoma causeing
obstruction of the vena cava and so puffiness of the face and neck
33- Patent ductus arterosis connecting aorta with left pulmonary vein
34-as we are increasing the precapillary resistance when flow will dec
and the filtration will decrease ....
35-Beta 1 increase renin secretion but alpha 1 decrease renin secretion.
36...
37 J
38-Cystic fibrosis patient have short stature
39-Did you noticed that when we add the drug X we need more histamine
to get the same response mean there is a revercible competitive
inhibitor there
...
40- its 30
41-discuss net ................
42- becuase there are bruit its mean there is atherosclerosis of the
renal artery .. less blood goes to the kidney and renin is secreted
which convert angiotensin 1 into angiotensin 2 and which in turn
increases aldosterone and increase Na absortion and so HTN.
43- Oxcytocin but what is the 2nd messenger of Oxcitocin?
44-PCOS clue is decreased FSH
45-B
46-net search today
47-We know that radiation induced thyroid papillary ca is most common
but can it be Laryngeal CA????
48-E but see notes
49-M blocker block secretion and so cause dry mouth ipratropium
50-the oral drugs pioglitazone and rosiglitazone can cause or
exacerbate heart failure and pulmonary edema and should be
avoided in patients with left ventricular dysfunction
(impaired pumping ability of the heart) or chronic renal
insufficiency.

BLOCK TWO
1-B seem to be right... when we add antibiotic resistance plasmid,
we can get the colonies who are resistance to a particular drug
and can eliminate the drug that are sensitive ...
2- C seem to be right as we see that in CF there is a defect
mutation and 508 codon is missing coding for Phenylalanine
amino acid .. in C only phenylalanine is shown there
3-Phenylalanine Hydroxylase deficiency leading to PTU....
4-Nondisjunction will produce either an egg with 24 chromosome or
with 22 chromsomes..
5-Acute pancreatitis so enzymatic fat necrosis
6-X linked recessive disease more common in male and if female
are symptomatic then its because of inactivation of more
maternal chromsome than paternal... female are homozygouys
for the abnormal chromosome.
7-A
8-Unstable mood , impulsiveness.. female more than male
9-here is a point never assist the patient to die ....
passively is ok but actively is not ok.... i think C seem to be right
10-D??
11-E
12-transplant patient often get CMV infection so Gancyclovir
13-A
14-CCR5 i% of US population give protection to HIV infection
15-B
16-D because IgG protect respiratory mucosa from infection

17-listen steven daughtery
18-D lack of ramdomization need explanations
19-see physio
20-A
21-polycythemia so F
22-c abducent nevre
23-Radial nevre
24-circle of willus
25-D should know from where various seizure arise in the brain
26-E can any body explain?
27- Cohesion BW adjacent cells ......... and held them togethers
28-D never problem
29-G
30-what is the diagnosis
31-D seem to be right
32-what is the diagnosis?
33-C
34-During exercise the heart rate increases and when HR reach 180
it compromise the coronary blood supply .. OK now pumping action
increases the heart metabolism and increases metabolite causes
coronary vasodilation..... and so increases blood flow. Now in
exercise increase work volume occur at same pressure so C
seem to be right
35- Aortic pressure will be less than ventricular pressure so
D seem to be right
36-D
but need to check
37-Parietal cell
38-E
39-F
40-c
41- see picture of renal ameyloidosis from google
42-F
43-B
44-history is relevent to adenocarcimona
45-Babies Blue Normal reaction to birth
46-E
47-D need to check lab value
48-D
49-C seem to be right ... physiostigmine enter CNS , neostigmine not so
when you have confusion about which enter then think N is for NOT ..
50- C

BLOCK 3
1- A/T rich region are where Histone bind to DNA, Nucleosome
are formed by the histone octamer plus DNA wound round it.
One nucleosome is connected to the other by H1 histone.
Need net search or discussion..
2-C release factor
3-Alanine is converted to pyruvate for Gluconeogenesis
4-F
5-reperfusion injury by free redical
6-Autosomal recessive
7-Gamma interferon secreted by Th1 cell causes Macrophages
activation and activated macrophages become fused to
form multinucleated giant cell
8-A
9-C but not sure need forum discussion
10-Vit. C
11-E
12-A
13-Alkylating agent
14-D as this virus is segmented so produces a number of band
need discussion
15-discussion
16- Pneumococcus encapsulated bacteria
17-this is a bar graph ok first you count how many are total children
so 25+30+35+10=100 now how many children have two episode of UTI?
answer 10 now out of hundred children 10 have two episode of UTI and
will be be 10 percent .
18-Case cantrol study
19-A
20-Aferican type of Burkit lymphoma classic picture of starry sky
appearance of histo slide associated with c myc oncongene..
21-B
22-F
23-A
24-E
25-D
26-C
27-A melanocyte are derivative of neural crest cell
28-Posterior cruciate ligament Tibia move posterioly while for anterior
cruciate ligament tibia move anteriorly
29-B polumyalgia rheumatica is associated with Temporal arteritis
30-A???
31-Type11 form new type 1 cells
32-Pneumothorax there will be Hyperresonant, deviation of tracha to
opposite plus decreased breath sound and absent fremitus
33-A
34-A
35-B
36-D but need discussion
37-C
38-F for hurshsprung disease symptoms appear soon after birht
39-A but how need explanation
40-Absent of kidney lead to oligohydoamnious
41- ADH causes increase water reabsorption so serum osmolarity
would Dec , Urine osmolarity inc and urine sodium conc will be high
42-F
43-A accessory nipple got inlarged due to Pregnency
44-Guljan says that
age MC tumor of gynae
45 Cervical
55 endometrial
65 Ovarians
Note CEO alphabat come accordingly
in the Q stem ist mention that she has PCOS mean has high estrogen
plus Height is normal mean she dont have tuner syndrome
which point to ovarian syndrome ... but its endometrial Ca
post menopausal bleeding
45-E
46-D PID
47-B
48-D due to parathyroid removal
49-need discussion
50-D but need to know whether is this a brush border enzyme??


BLOCK 4
1-A
2-D need clarification
3-Need to see YH biology notes C?
4-A action potential travel to the interior of myocyte due to
T tubule
5-its X linked recessive mean only diease gene on X chromosome
and if that male parent would have defective gene on his X
chromosome then he would have the disease and he dont have
its mean that he is not carrier of this disease
6-B
7-need clarification from YH biology notes
8-B??
9-A not congenital because he is 70 year old
10-Partial agonist as at low dose its acting as agonist but
at high dose its acting as antagonist.
11-A
12-Penecillin are excreted by kidney so when renal
function are compromised then serum drug level increse as this y
patient
13-D
14-B
15-E
16-C but what is ghost cell?
17-Need mastering of Biostatistics
18-Thymus
19-E
20-A but need to check
21-A
22-Cerebellum and in cerebellum has ipsilateral signs
23-E
24-Duodenal atresia and ths diagnosis seem to be hurshsprug disease
25-E
26-B but need to check this nusty Q
27-B
28- D increase blood circulation
29-need to discuss A?
30-H
31-E
32-G DVT
33-E
34-D
35-A but need to memorise the time sequence of infarction
36-A
37-A but how to differentiate between the rest of conditions
38-cirrhosis and increase in splenic vein pressure due to portal
hypertension
39-B need to revise all the antihelmeitic drugs
40-what is the main function of mesengial cell....
41-C
42-i think E but some says c
43-B because for outlet incontenence there is continouse voiding
without a stress factor
44-5 alpha reductase convert testosterone into DHT which is necessary
for the development of external ganitalia including prostate
when DHT is not formed female external feature are formed but
internal male system is developed because testosterone is required to
form normal internal male struture .
45-E
46-An inhibitory hormone so inhibit all the function
47- Diabetic ketoacidosis mucor specific
48-C
49-C
50-Spironolactone aldosterone antagonist...

Corrections
block1
2.D
5.D
7.E
9.D
10.D
14.B
21.H
23.A
24.A
28.B
29.E
35.E
38.C
39.B
40.A
45.B
46.C
48.E
block2
2.C
4.D
10.C
22.C
28.A
31.D
38.E
41.D
45.A
46.E
49.C
block3
2.C
4.F
8.A
9.E
15.C
16.E
25.E
26.C
29.B
30.A
41.B
43.A
48.D
block4
3.C
4.A
5.A
20.A
21.A
22.D
34.D
36.A
40.C
42.E
46.E
49.C

[ArchivalUser]

nbme 5
Block 1
1 A
2D
3E
4A
5B
6A
7B
8B
9A
10D
11B
12B
13B
14B
15A
16A
17B
18E
19F
20C
21B
22D
23B
24C
25A
26E
27A
28D
29E
30B
31A
32D
33E
34C
35D
36E
37B
38G
39A
40A
41E
42A
43A
44C
45F
46B
47D
48D
49B
50C
Block 2
1E
2D
3F
4B
5D
6B
7D
8B
9B
10B
11E
12E
13A
14B
15B
16E
17F
18C
19C
20A
21D
22F
23F
24C
25A
26E
27D
28C
29D
30E
31A
32A
33B
34E
35A
36B
37E
38E
39F
40E
41A
42D
43A
44E
45D
46E
47D
48F
49A
50E
block 3
1C
2E
3D
4A
5E
6A
7A
8D
9D
10C
11C
12D
13D
14B
15C
16A
17E
18C
19B
20C
21E
22E
23B
24E
25B
26C
27A
28C
29C
30B
31D
32D
33D
34E
35E
36C
37B
38C
39D
40E
41D
42B
43B
44E
45D
46H
47A
48D
49E
50C
block 4
1A
2C
3E
4C
5D
6F
7D
8B
9C
10B
11E
12E
13F
14E
15C
16B
17D
18A
19A
20D
21A
22D
23C
24C
25A
26D
27C
28F
29F
30A
31C
32C
33C
34C
35G
36B
37C
38E
39D
40A
41E
42D
43D
44D
45C
46D
47A
48D
49E
50C

[ArchivalUser]

nbme 6
block1
1. C
2. I
3. C
4. A
5. D
6. A
7. A
8. C
9. D
10. H
11. A
12. B
13. F
14. E
15. D
16. D
17. A
18. A
19. A
20. E
21. E
22. C
23. D
24. A
25. C
26. A
27. C
28. D
29. D
30. A
31. A
32. C
33. D
34. C
35. B
36. B
37. A
38. C
39. F
40. D
41. B
42. E
43. D
44. D
45. B
46. A
47. B
48. E
49. C
50. D
block 2
1. C
2. E
3. C
4. E
5. B
6. C
7. C
8. A
9. B
10. E
11. A
12. C
13. B
14. E
15. A
16. B or D?
17. B
18. G
19. D?
20. A
21. B
22. D orF?
23. A
24. C
25. D
26. A
27. B
28. B?
29. C?
30. E
31. B
32. B
33. E
34. B
35. C
36. A
37. B
38. D
39. A
40. D
41. A
42. B
43. E
44. E
45. B
46. F
47. A
48. A
49. E
50. A
block 3
1 B
2 C
3 E
4 B
5 B ?
6 B
7 D
8 E (corrected after)
9 B
10 A
11 E (have no idea)
12 F
13 C ?
14 B
15 C
16 B
17 B ?
18 B
19 D
20 B ?
21 D
22 B
23 C
24 B
25 A (corrected after)
26 E
27 C
28 C ?
29 A
30 D ?
31 E
32 D
33 C ?
34 C ?
35 A
36 H
37 D
38 E (corrected after)
39 D
40 A
41 B
42 A ??
43 A
44 E
45 C
46 E
47 E
48 B ?
49 H
50 D ??
block 4
1. E
2. A
3. C
4. C
5. D
6. B
7. A
8. A
9. D
10. D
11. C
12. C
13. C
14. A
15. D
16. A
17. F
18. E
19. D
20. H
21. E
22. B
23. B
24. B
25. C
26. A
27. B
28. D
29. A
30. B
31. A
32. F
33. D
34. B
35. C
36. A
37. B
38. F
39. D
40. C
41. E
42. B
43. A
44. D
45. B
46. D
47. C
48. D
49. D
50. I

[ArchivalUser]

u r welcome n good luck