Question.......................... - psychmledr

[ArchivalUser]

Thanx everyone for such a nice discussion....Iam writng it down in my FA......Thank you.....

[ArchivalUser]

Welcome, Swamy

[ArchivalUser]

Q1. Match the corresponding letters in the three columns

A. t ( 14; 18)
B. t ( 9;22)
C. t ( 11;14)
D. t ( 8;14)

1. Mantle cell lymphoma
2. Burkitt lymphoma
3. Follicular lymphoma
4. CML

i. Apoptosis inhibition
ii. transcription activation
iii. Tyrosine kinase up regulation
iv. Regulation of G1 to S phase transition

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Q2. Molecular studies on an abdominal lymph node containing lymphoma demonstrate t(2;8)(p12;q24) translocation. This is most compatible with which of the following diseases?

A. Burkitt's lymphoma
B. Mantle cell lymphoma
C. Multiple myeloma
D. Small cell lymphoma
E. Small cleaved cell lymphoma

[ArchivalUser]

Q1-A-3-1 Follicular lymphoma
B-4-111 CML
C-1-1111 Mantle cell lymphoma
D-2-11 Burkitts lymphoma

Q2-Small cell lymphoma?
Once again thanx psychmledr...Have a great day...

[ArchivalUser]

Hi swamy. You are welcome. Do have a great day too


Q1. Correct. Good job

Q2. Incorrect. Please try again.

The right answer is new to me too, so wanted to share it.

[ArchivalUser]

Is it E-Small cleaved cell lymphoma?...Thank u...

[ArchivalUser]

Once again thanx a lot for trying to teach new thing to everyone....

[ArchivalUser]

2nd: E?
Thank you for the question

[ArchivalUser]

The answer to Q2 is "A".......Burkitt's Lymphoma

t(8;14) is the most common translocation, seen in about 85% of cases: involves c-myc and Ig Heavy chain

But there are 2 more variants which are seen in the other 15% of cases:

t(2;8)(p12;q24) and t(8;22)(q24;q11)

t(2;8)(p12;q24) is c-myc and Kappa Light Chain

t(8;22)(q24;q11) is c-myc and Lambda Light Chain

You can remember them as t(2;8) and t(8;22)

[ArchivalUser]

Thank you psychmledr....This is new for me. Thank you !!