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64. A newborn presents with severe acidosis, vomiting, hypotonia, and neurologic deficits. Serum analysis reveals elevated levels of lactate and alanine. These observations suggest a deficiency in which of the following enzymes?
A. Alanine aminotransferase
B. Glutamate dehydrogenase
C. Lactate dehydrogenase
D. Pyruvate carboxylase
E. Pyruvate dehydrogenase
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hey girls,i was thinking couldn't it be E???
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no pyruvate carboxylase ....no gluconeogenesis...pyruvate has to be converted to alanine n lactate
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I chose D as well. However, Kaplan chooses E. Explanation is that the symptoms are not consistent with PCD.
I did some research online and found out that both diseases have similar clinical symptoms. My conclusion is that this Q is not well written.
Answers for you guys confirm my hypothesis. thanks
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if kaplan says PD is corect then it must be corect
