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A 7-year-old girl develops a fever, conjunctivitis, photophobia, and a cough. Her pediatrician notes white spots on a bright red background on the girl's buccal mucosa. Within days, a rash begins around the hairline, then spreads to the trunk and extremities. One week later, the child suddenly begins to convulse, and loses consciousness. She is taken to the emergency room, where involuntary movements and pupillary abnormalities are noted. Which of the following would most likely be seen on CNS biopsy?
A. Demyelination of white matter of cerebral hemispheres with abnormal giant oligodendrocytes
B. Perivenous microglial encephalitis with demyelination
C. Phagocytosis of motor neurons in the spinal cord
D. Severe hemorrhagic and necrotizing encephalitis of the temporal lobe with eosinophilic Cowdry type A inclusion in neurons and glia
E. Small granulomas with central caseation in the meninges
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back,
14 the answer I gave was EEEEEE , was just comparing the choice on neovascularization.
15) whats the explantion?
17 )would also have chosen A SSPE, like durham but maybe B
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17 B
thanks for giving me another chance.
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15.) Check that
http://findarticles.com/p/articles/mi_m0..._n15677755
17.) The correct answer is B. The initial history given is classic for measles, with the appearance of Koplik's spots (white spots on the buccal mucosa) followed by a rash beginning along the neck and hairline and spreading to the trunk and extremities. The sequela this child is experiencing is post-infectious encephalomyelitis, which can follow either infection with measles, varicella, rubella, mumps, or influenza, or vaccination with vaccinia vaccine or rabies vaccine derived from nervous tissue. Treatment is supportive, with a mortality of 15 to 40%; survivors frequently have significant permanent neurologic deficits. The pathologic finding is perivenous microglial involvement with demyelination.
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18.) A 82“year-old diabetic is involved in an automobile accident, with severe thoracic and abdominal traumatic injuries. He is rushed to the hospital and placed in the intensive care unit. After a few hours, there is the rapid onset of myocardial dysfunction, hypotension, disseminated intravascular coagulation, and coma. This sequence of events most closely mimics what type of shock?
A. Anaphylactic
B. Cardiogenic
C. Hypovolemic
D. Neurogenic
E. Septic
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pt the key point.u must be careful to differeniate between others when u read fasttttttt,make silly mistakesss
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"vaccination with vaccinia vaccine or rabies vaccine derived from nervous tissue. "-how is it
causing it?
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