09-03-2008, 11:46 AM
_ A 26-year-old man has a 4-week history of increasingly severe bloody diarrhea, urgency, tenesmus, and abdominal pain without fever, chills, or excessive sweating. The patient has an 8-pack-year smoking history.
On physical examination, he appears well. The abdomen is mildly tender without guarding or rebound. Rectal examination is normal. Hemoglobin is 12 g/dL (120 g/L), the leukocyte count is 11,300/μL (11.3 × 109/L), and the erythrocyte sedimentation rate is 38 mm/h. Colonoscopy shows areas of inflammation throughout the colon associated with friability, granularity, and deep ulcerations. The inflamed areas are separated by relatively normal-appearing mucosa, including normal rectal mucosa. The ileum appears normal. Biopsy samples from the inflamed areas of the colon show moderately active chronic colitis without granulomas. Biopsy samples from the ileum are normal.
a. Crohn disease
b. Ulcerative colitis
c. Microscopic colitis
d. Yersinia enterocolitis
e. Ischemic colitis
On physical examination, he appears well. The abdomen is mildly tender without guarding or rebound. Rectal examination is normal. Hemoglobin is 12 g/dL (120 g/L), the leukocyte count is 11,300/μL (11.3 × 109/L), and the erythrocyte sedimentation rate is 38 mm/h. Colonoscopy shows areas of inflammation throughout the colon associated with friability, granularity, and deep ulcerations. The inflamed areas are separated by relatively normal-appearing mucosa, including normal rectal mucosa. The ileum appears normal. Biopsy samples from the inflamed areas of the colon show moderately active chronic colitis without granulomas. Biopsy samples from the ileum are normal.
a. Crohn disease
b. Ulcerative colitis
c. Microscopic colitis
d. Yersinia enterocolitis
e. Ischemic colitis