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nbme2- - biochem510
#1
33.) An asymptomatic 52-year-old man comes for a
follow-up
examination 1 month after he passed renal calculi. He
has a history of renal
calculi 2 years ago. Serum uric acid and calcium
levels and urinary
oxalate excretion are within normal limits. Urinary
calcium excretion is
increased. In order to avoid recurrence of renal
calculi, which of the
following is the most appropriate pharmacotherapy for
this patient?

A
) Bicarbonate

B
) Calcium lactate

C
) Methenamine mandelate

D
) Probenecid

E
) Thiazide diuretic


34.

A 57-year-old woman is brought to the emergency
department because of
abdominal pain for 12 hours. Over the past 3 hours,
the pain has become
severe and generalized. Over the past month, she has
had mild upper
abdominal discomfort that is relieved by eating. She
has a history of
recurrent migraines treated with sumatriptan as
needed. Her temperature
is 38.2 C (100.8 F), blood pressure is 170/95 mm Hg,
and pulse is
110/min. Abdominal examination shows mild distention;
there is marked
rigidity with diffuse tenderness. Bowel sounds are
absent. Rectal
examination shows no abnormalities; test of the stool
for occult blood is
negative. Laboratory studies show:


Hematocrit 36%
Leukocyte count 16,500/mm3
Serum
Na+ 145 mEq/L
Cl“ 106 mEq/L
K+ 3.8 mEq/L
HCO3“ 19 mEq/L
Urea nitrogen (BUN) 32 mg/dL

Which of the following is the most appropriate next
step in diagnosis?

A
) X-ray films of the abdomen while supine and
standing

B
) Abdominal ultrasonography

C
) Upper gastrointestinal series with contrast

D
) HIDA scan

E
) Fiberoptic endoscopy of the upper
gastrointestinal tract
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#2
E
C
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