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a 34-year old man who is a track driver in Oklahoma collides with a deer on the highway. He takes the deer home and butchers it. Five days later, he develops a fever, nonproductive cough, shortness of breath, and generalized lymphadenopathy. Physical exam: no skin lesions. Which of the following is most likely to occur during this patient's illness?
A. Arthus reaction
B. Cytotoxic hypersensitivity
C. Mast cell degranulation
D. Neutrophilia
E. Type 4 hypersensitivity
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Francisella tularensis is an intracellular bacterium, meaning that it is able to live as a parasite within host cells. It primarily infects macrophages..
Antonella
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The answer is E. Tularemia can cause pneumonia like symptoms if inhaled. Since Francisella infects macrophages, it will cause a Th1 response which is what a delayed or Type IV hypersensitivity activates.
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