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when to give ace(-)tor - docmus
#1
In post MI / In Heart failure??? within 24hours/ 2-3 days later??
thanks
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#2
u can start within 24 hrs.

Overall, ACE inhibitors provide symptomatic improvement
in patients with NYHA functional class II-IV failure and improve
mortality in patients with moderate and severe heart failure. In
asymptomatic patients, ACE inhibitors prevent onset of heart failure
and reduce the need for hospitalization.
•• ACE inhibitors decrease afterload, decrease sodium retention,
and directly reduce adverse biologic effects on myocytes.
•• ACE inhibitor use decreases mortality in patients with moderate
and severe heart failure.
•• ACE inhibitors provide symptomatic improvement in patients
with NYHA class II-IV heart failure symptoms.
•• In asymptomatic patients, ACE inhibitors reduce the incidence
of heart failure and reduce the need for hospitalization.
ACE inhibitors are given initially in small doses because of possible
hypotensive effects. Dosage should be titrated up as tolerated on the
basis of symptoms and blood pressure, potassium, and creatinine
measurements. Even if a patient is clinically compensated on a low
or intermediate ACE inhibitor dose, upward dose adjustment as
tolerated is beneficial. For optimal ACE inhibitor doses to be achieved,
the diuretic dose may need to be reduced. Common side effects of
ACE inhibitors include hypotension, hyperkalemia, azotemia, cough,
angioedema (mild or severe), and dysgeusia. The benefits and potential
side effects of ACE inhibitors are thought to be a class effect.
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#3
for heart failure, once u diagnose, then u can start
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#4
nice! thanks!
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