Digoxin toxicity-Hyperkalemia or hypokalemia? - ydeng

[ArchivalUser]

From UW -Digoxin toxicity is Hyperkalemia; but by Kalplan, Digoxin toxicity is Hypokalemia.
Which one is correct, why? Thanks.

[ArchivalUser]

Digoxin results in Hyperkalemia but Hypokalemia increases toxicity of Digoxin

[ArchivalUser]

digoxin inhibits Na-K Atpase. so k+ remains outside cells resulting in hyperkalemia. therefore, hyperkalemia is a result of digoxin use.
normally digoxin and K+ compete to combine with Na K ATPase.
but if hypokalemia is present previously, more digoxin can easily bind and act on the pumps. so all its effects are increased even with the same dose. this results in toxicity of digoxin.

[ArchivalUser]

I found this medication extremely helpful when I was first diagnosed. I had to change my eating habits dramatically, so when I messed up or when the nausea flared up Reglan was great. Know more here http://www.internationaldrugmart.com/met...amide.html