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25yr old lady (type A, Rh -ve) gives birth to a type A Rh +ve dude. Which of the following should be administered to the mom after birth to prevent disease of the newborn?
A. Active immunization to induce anti-Rh IgM antibodies
B. Active immunization to induce anti-Rh IgG antibodies
C. Active immunization to remove Rh antigen
D. Passive immunization to remove Rh Antigen
(NBME 6.4.26)
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Why is it DD??
Why not BB ??
Don't u give her antibodies ???
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plz some 1 explain this concept to me guys...
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Where is my panel of Experts today ???
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Every one partying tonight ?
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Hi Kindmd
You give her anti Rho Gam which is Anti-D Ab. This is clear any of the baby's antigen whcich may have entered her circulation during delivery. The thing is you dont want to induce memory because if you do that then if she has a second baby thats positive her body will recognize the antigen and react. So by giving passive immunization and clearing the antigen you prevent an actual immune response. Hope this helps!
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u got it ?
When u give "Pre made Antibodies", it is called "Passive Immunization" .... as the case here.
