12-24-2013, 12:58 AM
A 17 yo male presents with passage of dark urine.he has had multiple bacterial infections over several years and has history of venous thromboses, including portal vein thrombosis in the previous year. a CBC shows a Hb conc of 9.8g/dl, Hct of 29.9%, MCV of 98fL, platelets 150000/uL, and WBC 3800/uL, with a differential count of 29 segment neutrophils, 1band, 64 lymphocytes, 10 monocytes and 1 eosinophil. he has a reticulocytosis. serum haptoglobin level is very low. a mutation in which of the following gene products could give rise to this clinical condition?
A) spectrin
B) Glucose 6 Phosphate Dehydrogenase
C) Phosphatidylinositol glycan A
D) B-globin chain
E) Factor V
will be back in a few hours with the answer. enjoy
A) spectrin
B) Glucose 6 Phosphate Dehydrogenase
C) Phosphatidylinositol glycan A
D) B-globin chain
E) Factor V
will be back in a few hours with the answer. enjoy