nbme 15 qs- please could you answer this question - mrmrpiro1205

[ArchivalUser]

40. A 45-year-old man comes to the physician for a follow-up examination 2 weeks after beginning treatment with hydrochlorothiazide for hypertension He says that he feels
faint, light-headed, and dizzy when he gets out of bed and when he rises from a seated position too quickly. His pulse is 75/min, respirations are 12/min, and blood
pressure is 130/85 mm Hg while supine. Physical examination shows no abnormalities. Which of the following sets of changes best characterizes changes in the
cardiovascular system as this man goes from the supine to the standing position?
Carotid Sinus Cerebral
Venous Return Baroreceptor Activity Blood Flow
A) Increase Increase Increase
B) Increase Increase decrease
C) Increase decrease Increase
D) Increase decrease decrease
E) decrease increase increase
F) decrease increase decrease
G) decrease decrease increase
H) decrease decrease decrease

[ArchivalUser]

A paper says "We chose the sample size to have an 80% power of detecting a 15% mean difference with a significance level (two-sided) of 5%." If there really is no
difference between the groups overall which of the following best represents the chance that the study will find a statistically significant difference, and what is this error called

a) 0% type l error
B) 0%, type II error
C) 5% type I error
D) Type II error
E) 15% Type l error
F) 15% type II error
G) 20% Type I error
H) 20% Type II error

[ArchivalUser]

An investigator wishes to test the hypothesis that a number of CD44 splice variants correlate with aggressive disease progression and risk of relapse in patients with
Hodgkin disease especially if the variant protein CD44 v10 is expressed . the investigator plans to retrospectively screen archives of fresh frozen tissue and paraffin embedded biopsy specimens from documented Hodgkin disease patients .Assuming the necessary reagents are available, which of the following methods would be the most effective in screening the archives for the variant protein?
A) Affinity column chromatography
B) Density gradient centrifugation
C) Immunohistochemistry
D) Northern blot
E) Polymerase chain reaction (PCR)
I) Reverse transcriptase PCR
H) Southern blot

[ArchivalUser]

Please guys could you answer these questions urgently ..Thanks.

[ArchivalUser]

first one - man stand ups, blood pools in legs thus decrease venous return, decrease venous return decreases preload and decreases cardiac output resuling in decrease baroreceptor activity and decrease cerebral blood flow

[ArchivalUser]

second one - satistical significance is the chance of making a type one error - CCCCC
out of first aid under type one error heading in beh sci section

[ArchivalUser]

last one immunohistochemistry

[ArchivalUser]

Thanks a lot whatsfordinner.