05-15-2014, 07:51 AM
what enzyme is important in peripheral conversion of T4 to T3? and whar drugs block this conversion?
|
q#7 endocrine - verymotivatedlearner
|
05-15-2014, 08:12 AM
good job - c5a
selenium dependent 5'-deiodinase inhibited by propylthiouracil and propranolol Some minimal effect on thyroid hormone production however also comes with Propranolol - which has two roles in the treatment of hyperthyroidism, determined by the different isomers of propranolol. L-propranolol causes beta-blockade, thus treating the symptoms associated with hyperthyroidism such as tremor, palpitations, anxiety, and heat intolerance. D-propranolol inhibits Thyroxine deiodinase, thereby blocking the conversion of T4 to T3, providing some though minimal therapeutic effect. |
| « Next Oldest | Next Newest » |