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Bug of the day - bugguy19
#91
clinically i think

loa loa( eye worm) ____________ pruritus + no blindness


Onchocerca volvulus__________ river blindness + itchy leopard rash
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#92
Thks
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#93
Haemoplilus ( haemoplilus = blood loving)

gram -ve rod
pleomorphic
no exotpxin
need specific factors for growth ( found in the blood)

1/ H.ducreyi
require only x factor (hematin) for growth
STD
painfull chancroid (syphilis is painless chancroid)
macrolide OR 3rd generation cephalocporine



2/ H.influezae type B

obliquate human parasite
respiratory route
requre both factor X and factor V
attachment pili + igA protease
capsule (+ve Quelling test)

ENcapsulated H. influenza cause______
meningitis epidemic in un vaccinated (3mo- 2 yrs)
acute epiglottitis
septic arthritis
sepsis (pt with non functioning spleen)
pneumonia

NON capsulated H. influenza cause______

otitis media
sinusitis

ttt_____________

2nd or 3rd generation cephalosporine
HIb vaccine
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#94
PUNCHSS Kill urease +ve..kleibsella got insideSmile
Non capsulated -no vaccine so child gets otitis media despite hib vaccineSmile
No jetplanesSad(
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#95
to day is our last group of gram -ve rods the

ENTEROBACTERIACEAE ..........

two sub group

1/lactose fermenter _______

( E.coli , klebsiella )

2/ non lactose fermenters________

( motile and producing H2S are salmonella ,proteus )

(non motile and not producing H2S are shigella and yersinia )








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#96
E.coli

Gram -ve rod
Facultative anaerobe
Lactose fermenter
Indole +ve
B-hemolytic

3 Ag✈✈✈✈✈✈✈
K Ag (capsule ) ,O Ag ( component of LPS ) , H Ag (flagella )

3 toxin ✈✈✈✈✈✈✈
LT (increase cAMP) , ST (increase cGMP ) ,shiga like toxin (inactivate s60 ribosomal subunit)

4 main infections ✈✈✈✈✈✈✈

1/UTI .....ttt by fluroquinolone
2/Neonatal meningitis/sepsis (2nd most common cause) ttt by 3rd generation cephalosporin
3/septicemia in hospitalized pt . ttt by fluroquinolone or 3rd generation cephalosporin
4/Gastroentritis...4 main subgroups......ttt rehydration+antibiotic


✈✈✈✈ETEC✈✈✈✈traveler diarrhea... non inflammatory ttt by TMP/SMX

✈✈✈✈EPEC✈✈✈✈ 2nd most common cause of infantile diarrhea ttt by flouroquinolone

✈✈✈✈EIEC✈✈✈✈✈inflammatory diarrhea (blood +pus+fever)

✈✈✈✈EHEC✈✈✈✈0157:H7 non inflammatory (blood ,no pus ,no fever), HUS





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#97
Thats nice and includes almost all.May be just one if I could add..#oxidase negative # colonises with green sheen on EMB.thank you for all your effortsSmile
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#98
Thank you for the important addition
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#99
Very important DECLARATION ____________________________





ALL ENTEROBACTERIACEAE are oxidase -ve Smile
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Klebsiella species

1/ K.granulomatis_______
gram -ve rod
capsule
obligate intracellular
granuloma inguinale (subcutenous genital nodule + beefy red ulcer that bleed easily)
sexual contact, fecal contamination
scraping of lesion +gimsa stain shows Donovan bodies
TMP/SMX OR tetracycline



2/K.pneumonia_________________
gram -ve rod
capsule
non motile
mucoid colonies
lactose fermenting

pneumonia in alcholic, ( currant jelly sputum , usually rt upper lobe, cavity formation )
nosocomial infections__ UTI
sepsis immunocopromized

ttt 3rd generation cephalosporine or ciprofloxacin




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