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NBME 2 block 2 Q 38 - stranger016
#1
A 67-year-old man comes to the physician because of a
2-month history
of progressive shortness of breath. He has had a
4.5-kg (10-lb) weight
loss over the past 4 months. He has not had chest
pain. He has
congestive heart failure treated with furosemide,
digoxin, and enalapril. He
has smoked two packs of cigarettes daily for 30 years.
He appears
alert and is in no acute distress. His temperature is
37.2 C (99 F), blood
pressure is 140/85 mm Hg, pulse is 84/min, and
respirations are 18/min.
Examination shows no jugular venous distention. There
is dullness to
percussion, and breath sounds are decreased at the
left base. Cardiac
examination shows a laterally displaced point of
maximal impulse, normal
S1 and S2, and an S3 at the apex. There is 1+ edema
over the
extremities. An x-ray film of the chest shows an
enlarged cardiac silhouette,
left hilar fullness, and a moderate-sized left pleural
effusion.
Thoracentesis yields straw-colored fluid. Laboratory
studies show:


Serum
Glucose 90 mg/dL
Protein 7 g/dL
Lactate dehydrogenase 300 U/L
Pleural fluid
pH 7.25
Glucose 75 mg/dL
Protein 4.5 g/dL
Lactate dehydrogenase 280 U/L
Leukocyte count 2000/mm3
Segmented neutrophils 15%
Lymphocytes 85%

A Gram's stain and acid-fast stains are negative for
any organisms.
Which of the following is the most likely cause of
this patient's pleural
effusion?

A
) Bacterial pneumonia

B
) Collagen vascular disease

C
) Congestive heart failure

D
) Malignancy

E
) Pulmonary embolus with infarction

F
) Viral pleuritis

i think the answer is viral pleurisy
any comments???
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#2
this is an exudate. Considering 4.5 kg weight loss, history of heavy smoking and hilar fullness in an elderly male I would think of malignancy.
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#3
pleurisy would also cause exudative effusion,so why not viral pleurisy?
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#4
hi i think its Malignancy..patient has a weight loss and has a long standing smoking history...according to the lab values the effusion is exudative...would appreciate more answer explanations..thanx for uploading the Qs...
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#5
is malignancy the reason for CXR showing hilar fullness??
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#6
yes stranger and also his weight loss, his smoking history and his age
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#7
ok thanks avice..
and also it cant be pleurisy as he does not have symptoms of pleurisy so probably malignancy is the right answer...
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