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nbme2 Q2 - mdkhayat
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10-18-2015, 03:45 PM
An asymptomatic 42-year-old man with essential hypertension is started on an angiotensin-converting enzyme inhibitor. Which of the following shows the most likely effect of treatment on circulating levels of aldosterone, renin, and bradykinin?
Aldosterone/Renin/Bradykinin A) ↓ ↓ ↓ B) ↓ ↓ ↑ C) ↓ ↑ ↑ D) ↑ ↑ no change E) ↑ ↑ ↑ F) ↑ ↑ ↓
10-18-2015, 05:17 PM
renin>>.angiotensinogen>>AT-1>>ACE>>AT II right
so with ACEI, everything before ACE enzyme is elevated, so includes AT1 and also renin. pls correct me if i m wrong
10-18-2015, 06:07 PM
@khayat Beside ↓ aldosterone & Ang II -> that INC plasma renin*. Can you tell me what may have (-)feedback mech on secretion* at arrow on slide http://i.imgur.com/uNYstul.png?1 ?
10-18-2015, 09:04 PM
@cardio69
hope you are doing great. i have gotten better from the last time i took advice from you but i m very very bad in molecular bio and i just hate dealing with that subject, which book do you suggest i get my hands on for that? |
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