03-16-2016, 10:08 AM
A 35-year-old man undergoes gastrectomy for gastric carcinoma Gross examination of the resected stomach reveals diffuse thickening without a discrete mass lesion. Microscopic exam shows an infiltration of signet-ring cells dispersed singly. Family history reveals that his father had a similar cancer at a young age. What gene is most likely to be mutated in this patient and his father?
A. APC
B. CDH1
C. MSH2
D. PMS2
E. p53
A. APC
B. CDH1
C. MSH2
D. PMS2
E. p53