03-18-2016, 04:38 PM
A 45-year-old woman presents with an insidious and progressive syndrome characterized by pain and tenderness in multiple joints, with joint stiffness on rising in the morning, and early afternoon fatigue and malaise. Joint involvement is symmetric, with the proximal interphalangeal and metacarpophalangeal joints especially involved. Physical examination reveals tenderness in nearly all inflamed joints. Which of the following laboratory abnormalities is most likely?
(A) Antibodies to double-stranded DNA
(B) IgM anti-IgG antibodies
© Urate crystals and neutrophils in synovial fluid
(D) Anti-DNAase B
(E) HLA-B27 antigen
(A) Antibodies to double-stranded DNA
(B) IgM anti-IgG antibodies
© Urate crystals and neutrophils in synovial fluid
(D) Anti-DNAase B
(E) HLA-B27 antigen