My journal--Exam on 2nd June! - littledoc123

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yes it is, littledoc123.

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Today I'll just read short sections from MTB--Oncology & Allergy-immuno.

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Serotonin vs neuroleptic

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Which HTN medication causes a rash?

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How do you treat serotonin syndrome?

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Hello frineds, getting back to studying today after 3 days of no studying...
One full day off seems like a luxury to study
plan to pull of 2 blocks today!!


WORKHARD SEROTONIN SYDROME

Clinical and laboratory features
The Hunter Criteria for serotonin syndrome (SS) are fulfilled if the patient has taken a serotonergic agent and has one of the following:
Spontaneous clonus
Inducible clonus and agitation or diaphoresis
Ocular clonus and agitation or diaphoresis
Tremor and hyperreflexia
Hypertonia
Temperature above 38°C and ocular clonus or inducible clonus


SS is a clinical diagnosis; no laboratory test can confirm the diagnosis. SS can manifest a wide range of clinical symptoms from mild tremor to life-threatening hyperthermia and shock.



Examination findings can include: hyperthermia, agitation, ocular clonus, tremor, akathisia, deep tendon hyperreflexia, inducible or spontaneous clonus, muscle rigidity, dilated pupils, dry mucus membranes, increased bowel sounds, flushed skin, and diaphoresis. Neuromuscular findings are typically more pronounced in the lower extremities.

Treatment
Discontinue serotonergic agents
Sedate using benzodiazepines (eg, lorazepam 1 to 2 mg IV per dose; 0.02 to 0.04 mg/kg/dose in children): goal is to eliminate agitation, neuromuscular abnormalities (eg, tremor, clonus), and elevations in heart rate and blood pressure; titrate dose to effect
Provide: oxygen (maintain SpO2 ≥94); IV fluids; continuous cardiac monitoring
Anticipate complications; in severe SS vital signs can fluctuate widely and rapidly
If benzodiazepines and supportive care fail to improve agitation and abnormal vital signs, give cyproheptadine (12 mg orally or by orogastric tube for initial adult dose; pediatric doses included in main text)
Treat patients with temperature >41.1°C with immediate sedation, paralysis, and endotracheal intubation; treat hyperthermia with standard measures; avoid antipyretics such as acetaminophen

FOR A ONE LINE ANSWER : It would be cyproheptadine

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Risk factors for toxoplasmosis
Treatment
Sx

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Samp2016 thanks

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@samp2016--good! 2 blocks a day is great infact!!

@workhard11--Most imp risk factor is HIV/immunocompromised. Rx is with pyrimethamine and sulfadiazine.

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Yeah also soil on vegetables fruits,(didn't know)
Undercooked meat, cat feces
-uw