Phenytoin - samideb12

[ArchivalUser]

Is phenytoin given to a 12 years old pt ?

[ArchivalUser]

i think so DOSAGE IN PAEDIATRICS:
Loading dose in an emergency:
15-20mg/kg (max 1.5gm) IV over 1 hour.
Initial maintenance, oral or IV:
2mg/kg 12 hourly (preterm); 3mg/kg 12 hourly (1st week of life), 8 hourly (2wk-4yr), 12 hourly (5-12 yr); 2mg/kg (usual max 100mg) 8 hourly (12 yrs)
remember also this -Drugs whose efficacy is impaired by phenytoin include:
corticosteroids, warfarin, frusemide, oral contraceptives, rifampin, and theophylline

[ArchivalUser]

the only C/I i remem- is a known teratogen. The syndrome consists of craniofacial anomalies (broad nasal bridge, cleft lip and palate, microcephaly) and a mild form of mental retardation (average IQ=71).

[ArchivalUser]

Thank you for explanation.I thought that phenobarb is preferred .